JAMES W. HOLLINGSWORTH; DOROTHY R. HOLLINGSWORTH, M.D.
Radioactive chromium in sodium chromate is adsorbed firmly on the hemoglobin of intact red cells, thereby tagging the cells. Such red cells were used by Sterling and Gray to measure total red cell volume,1 and by Ebaugh, Emerson and Ross to study the survival of erythrocytes in vivo.2
In the past, the hemolytic element of the anemia of chronic infections has been investigated only by the measurement of pigment excretion, which was found to be normal.3 No studies of erythrocyte lifespan in patients with tuberculosis have been reported. Berlin4 has measured red cell volume in patients with tuberculosis, using radioactive
HOLLINGSWORTH JW, HOLLINGSWORTH DR. STUDY OF TOTAL RED CELL VOLUME AND ERYTHROCYTE SURVIVAL USING RADIOACTIVE CHROMIUM IN PATIENTS WITH ADVANCED PULMONARY TUBERCULOSIS(STUDY OF TOTAL RED CELL VOLUME AND ERYTHROCYTE SURVIVAL USING RADIOACTIVE CHROMIUM IN PATIENTS WITH ADVANCED PULMONARY TUBERCULOSIS*). Ann Intern Med. 1955;42:810–815. doi: 10.7326/0003-4819-42-4-810
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Published: Ann Intern Med. 1955;42(4):810-815.
Infectious Disease, Mycobacterial Infections, Pulmonary Tuberculosis, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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