W. L. JACK EDWARDS, M.D.; WILLIAM F. LUMMUS, M.D.
Spontaneous hypoglycemia was first described by Seale Harris1 in 1924, under the name of "hyperinsulinism." More recently, Conn2 has classified the hypoglycemias, naming "functional hyperinsulinism" as including those forms of hypoglycemia not associated with anatomic lesions. The majority of patients in this group have associated anxiety states, with spontaneous hypoglycemic attacks at least one to two hours after meals. The term now commonly used for this disorder is "functional hypoglycemia."
This report is concerned with patients having functional hypoglycemia in a series of 866 referred ambulatory patients. Since the hyperventilation syndrome was found to occur concomitantly in more than
EDWARDS WLJ, LUMMUS WF. FUNCTIONAL HYPOGLYCEMIA AND THE HYPERVENTILATION SYNDROME: A CLINICAL STUDY12. Ann Intern Med. ;42:1031–1040. doi: 10.7326/0003-4819-42-5-1031
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Published: Ann Intern Med. 1955;42(5):1031-1040.
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