ALBERT B. SAREWITZ, M.D.
The widespread use of the broad spectrum antibiotics has intensified the problem of clinical infections caused by Candida albicans.1 These infections—moniliasis of the mouth, vulvovaginal mucosa, intertriginous areas of the skin, and the nails—have been common and persistent in the face of many modes of therapy. The recognition that some of the broad spectrum antibiotics enhance the virulence of C. albicans and result in its systemic dissemination has made the search for effective anti-monilial agents one of great importance.2, 3 Such an agent might effectively prevent the aggravated and even fatal fungus infections which have been reported as having complicated
SAREWITZ AB. TREATMENT OF GENITOURINARY MONILIASIS WITH ORALLY ADMINISTERED NYSTATIN1. Ann Intern Med. ;42:1187–1189. doi: 10.7326/0003-4819-42-6-1187
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Published: Ann Intern Med. 1955;42(6):1187-1189.
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