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It was announced in 1943 that certain of the flavonoids isolated from plant sources would in some cases restore to normal capillaries with increased fragility. Since the active material was concerned with capillary permeability and was believed at first to be a dietary essential, it was designated as Vitamin P. However, the status of these compounds as vitamins is by no means certain; therefore they should be described as flavonoids rather than as Vitamin P, although in medical literature the latter term is commonly used.
This book presents an evaluation of the clinical research on rutin, its pharmacology and chemistry.
Rutin and Related Flavonoids: Chemistry, Pharmacology, Clinical Applications.. Ann Intern Med. ;42:1335–1336. doi: 10.7326/0003-4819-42-6-1335_2
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Published: Ann Intern Med. 1955;42(6):1335-1336.
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