MARVIN A. LINDER, M.D.
Periodic paralysis, a relatively uncommon disease first reported by Musgrave55 in 1727, has recently been reported to occur in conjunction with hyperthyroidism.
Periodic paralysis as described by Talbott55 is characterized by intermittent attacks of flaccid paralysis of the muscles of the extremities, with loss of both deep tendon reflexes and response to electrical stimulation of motor nerves39 without mental impairment. The paralysis begins peripherally, progressing centrally with more profound involvement of the extensor muscles of the legs than of the flexors. Rarely, the paralysis may involve the muscles of deglutition, phonation and the extra-ocular muscles causing blurring of vision. Other
LINDER MA. PERIODIC PARALYSIS ASSOCIATED WITH HYPERTHYROIDISM: REPORT OF THREE CASES1. Ann Intern Med. ;43:241–254. doi: 10.7326/0003-4819-43-2-241
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Published: Ann Intern Med. 1955;43(2):241-254.
Endocrine and Metabolism, Thyroid Disorders.
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