ROBERT LLOYD SEGAL, M.D.
Of all diuretic drugs, the mercurial diuretics have the established advantage of combining effectiveness and safety when administered intramuscularly.1 They may on occasion cause local or generalized reactions of varying degree. Chemical modifications of these organic mercurial compounds have been employed in an effort to minimize such toxic effects.2, 3 Another mercurial compound, mercaptomerin sodium (Thiomerin) has recently been introduced. This preparation is an organic mercurial combined with a mercaptan (disodium salt of N-(gamma-carboxy-methyl-mercaptomercuri-beta-methoxy) propyl camphoramic acid). Formula: C(CH3), C(COONa) (CH3), CH2, CH2, CH(ONH CH2) CH (OCH2) CH2HgSCH2.
The stated clinical characteristics of mercaptomerin are:
1. It is an effective
SEGAL RL. TOXIC REACTION TO MERCAPTOMERIN (THIOMERIN): CASE REPORT1. Ann Intern Med. ;43:435–441. doi: 10.7326/0003-4819-43-2-435
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Published: Ann Intern Med. 1955;43(2):435-441.
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