T. T. MACKIE, M.D., F.A.C.P.; J. W. MACKIE, M.B.; C. M. VAUGHN, Ph.D.; N. N. GLEASON, M.S.; B. G. GREENBERG, Ph.D.; E. S. NENNINGER, B.S.; M. N. LUNDE, M.P.H.; L. L. A. MOORE JR., M.S.; J. A. KLUTTZ; M. O. TALIAFERO, A.B.
Since Kofoid's1 original report of an instance of familial infection by Entamoeba histolytica in 1923, evidence has gradually accumulated pointing to the family unit as an important element in the epidemiology of amebiasis. Shortly thereafter, a similar example of multiple infection in a family group was reported from Panama.2 It was during the 1930's, however, that greatest attention was directed to prevalences within the domestic circle. In the course of a community study in Tennessee, 23 of 27 individuals comprising five families were found to be infected.3 A study in Italy reported infection in seven members of a family of
MACKIE TT, MACKIE JW, VAUGHN CM, GLEASON NN, GREENBERG BG, NENNINGER ES, et al. INTESTINAL PARASITIC INFECTIONS IN FORSYTH COUNTY, NORTH CAROLINA. II. AMEBIASIS, A FAMILIAL DISEASE1. Ann Intern Med. ;43:491–503. doi: 10.7326/0003-4819-43-3-491
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Published: Ann Intern Med. 1955;43(3):491-503.
Gastroenterology/Hepatology, Infectious Disease.
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