HUGH CHAPLIN JR., M.D.
The hazards of "dangerous universal donor" blood have received considerable attention in recent years. Because of increasing awareness of this problem, and in the light of occasional serious and even fatal reactions caused by the emergency transfusion of blood or plasma containing high anti-A or anti-B antibody titers,1-6 it has been recommended that some sort of screening procedure be employed in the selection of Group O blood suitable for transfusion to heterospecific recipients. A procedure commonly used is to test the capacity of the donor's serum diluted 1/200 in saline to agglutinate an equal volume of 2% saline suspension of
CHAPLIN H. HEMOLYTIC TRANSFUSION REACTION ASSOCIATED WITH THE TRANSFUSION OF "DANGEROUS UNIVERSAL DONOR" BLOOD1. Ann Intern Med. ;43:1334–1340. doi: 10.7326/0003-4819-43-6-1334
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Published: Ann Intern Med. 1955;43(6):1334-1340.
Hematology/Oncology, Prevention/Screening, Red Cell Disorders.
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