ROBERT C. HENDRIX, M.D.; DONALD M. GOOD, M.D.
Fibrocystic disease of the pancreas (mucoviscidosis) has properly been considered a disease of infancy and early childhood. Clinical manifestations are usually evident very early in life. Death had occurred within the first year in about 70% of the cases reported by Andersen1 in 1938. This early clinical appearance, the familial pattern so often exemplified, and the advanced morphologic lesions even in infants make it probable that there is an intrinsic element in pathogenesis which may be effective even before birth.
Before 1938, many cases of fibrocystic disease which now could be recognized with ease were reported under various names and
HENDRIX RC, GOOD DM. FIBROCYSTIC DISEASE OF THE PANCREAS AFTER CHILDHOOD: CASE REPORT WITH NECROPSY AT 17 YEARS1. Ann Intern Med. ;44:166–173. doi: 10.7326/0003-4819-44-1-166
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Published: Ann Intern Med. 1956;44(1):166-173.
Gastroenterology/Hepatology, Pancreatic Disease.
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