JOHN C. BUCHANAN, M.D.; BYRD S. LEAVELL, M.D., F.A.C.P.
Pseudohemophilia is a hemorrhagic disorder which, occurring in either sex, is distinguished essentially by a bleeding tendency and by the single laboratory abnormality of a prolonged bleeding time. The clotting time, platelet count and prothrombin time are normal, and clot retraction is usually normal. The tourniquet test is positive in about half of the patients with this disease. Though often occurring sporadically, pseudohemophilia is familial in a high percentage of cases.
Interest in this hemorrhagic diathesis was stimulated a quarter of a century ago by von Willebrand's reports1-3 in which he described a bleeding tendency observed in 16 female and
BUCHANAN JC, LEAVELL BS. PSEUDOHEMOPHILIA: REPORT OF 13 NEW CASES AND STATISTICAL REVIEW OF PREVIOUSLY REPORTED CASES(PSEUDOHEMOPHILIA: REPORT OF 13 NEW CASES AND STATISTICAL REVIEW OF PREVIOUSLY REPORTED CASES*). Ann Intern Med. 1956;44:241–256. doi: 10.7326/0003-4819-44-2-241
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Published: Ann Intern Med. 1956;44(2):241-256.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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