EDMUND L. DUBOIS, M.D.; STUART MARTEL, M.D.
Although it is generally accepted that the various forms of lupus erythematosus are merely different manifestations of the same disease, the most common variety; namely, the chronic discoid form, has been regarded as primarily a localized manifestation whose systemic changes are either absent or missed. The object of this study is to point out that these generalized changes are very common in discoid lupus and have hitherto been overlooked.
Chronic discoid lupus is characterized by skin lesions which in the active phase consist of erythematous plaques of varying sizes with scaling, follicular plugging, followed in the healing stages by atrophy
DUBOIS EL, MARTEL S. DISCOID LUPUS ERYTHEMATOSUS: AN ANALYSIS OF ITS SYSTEMIC MANIFESTATIONS1. Ann Intern Med. 1956;44:482–496. doi: 10.7326/0003-4819-44-3-482
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Published: Ann Intern Med. 1956;44(3):482-496.
Lupus Erythematosus, Rheumatology.
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