R. F. WETTINGFELD, M.D.; JOHN ROWE, M.D.; DON E. EYLES, SC.D.
In the short space of 16 years since toxoplasmosis was first recognized as a disease in human beings, great strides have been made in delineating the various clinical syndromes, pathology and diagnosis of the disease. A dynamic interest in all the clinical and investigative aspects of this disease continues to reduce the gaps in our knowledge. Of the unsolved clinical problems in toxoplasmosis, the need for effective therapy is one of the greatest. While extensive laboratory investigation has disclosed agents of modest efficacy, the paucity of cases, especially those recognized sufficiently early, has made clinical corroboration difficult.
We recently observed
WETTINGFELD RF, ROWE J, EYLES DE. TREATMENT OF TOXOPLASMOSIS WITH PYRIMETHAMINE (DARAPRIM) AND TRIPLE SULFONAMIDE1. Ann Intern Med. ;44:557–564. doi: 10.7326/0003-4819-44-3-557
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Published: Ann Intern Med. 1956;44(3):557-564.
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