ENRIQUE SAHAGUN, M.D.; R. O. BURNS, M.D.
Perforation of the interventricular septum occurring as a fatal complication of acute myocardial infarction was first described by Latham1 in 1845. The first antemortem diagnosis was made by Brunn2 in 1923. Since that time numerous authors have reported cases, raising the total to approximately 100 at the present date. Thirty-six of these cases were diagnosed ante mortem.
Sager in 19343 pointed out the relative simplicity of the diagnosis, and emphasized the significance of the sudden appearance of a loud precordial systolic murmur and thrill in a patient with a recent myocardial infarction.
Numerous large autopsy series of deaths due
SAHAGUN E, BURNS RO. PERFORATION OF THE INTERVENTICULAR SEPTUM FOLLOWING ACUTE MYOCARDIAL INFARCTION: A REPORT OF FOUR CASES DIAGNOSED ANTE MORTEM1. Ann Intern Med. ;44:657–667. doi: 10.7326/0003-4819-44-4-657
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Published: Ann Intern Med. 1956;44(4):657-667.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
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