CAROLINE BEDELL THOMAS, F.A.C.P.; JOHN LAURENS BATEMAN; EVAN FLORIAN LINDBERG; HAROLD J. BORNHOLD
There is increasing evidence that smokers suffer from coronary artery disease somewhat more frequently than nonsmokers.1-4 The reason for such an association is not known. English, Willius and Berkson first demonstrated the statistical validity of this finding in 1940, when they compared the records of 1,000 smokers and 1,000 nonsmokers and found a significantly higher incidence of coronary artery disease among smokers 40 to 59 years old than among nonsmokers of comparable age.1 The authors expressed the belief that "in all probability the smoking of tobacco was not an etiologic factor but was perhaps an influence that affected the
THOMAS CB, BATEMAN JL, LINDBERG EF, BORNHOLD HJ. OBSERVATIONS ON THE INDIVIDUAL EFFECTS OF SMOKING ON THE BLOOD PRESSURE, HEART RATE, STROKE VOLUME AND CARDIAC OUTPUT OF HEALTHY YOUNG ADULTS12. Ann Intern Med. 1956;44:874–892. doi: 10.7326/0003-4819-44-5-874
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Published: Ann Intern Med. 1956;44(5):874-892.
Cardiac Diagnosis and Imaging, Cardiology, Coronary Risk Factors, Smoking, Tobacco, Alcohol, and Other Substance Abuse.
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