KJELD O. HUSEBYE, M.D.; J. M. STICKNEY, M.D.; WARREN A. BENNETT, M.D.
Capillary thrombosis is observed in a number of conditions. Extensive involvement has been reported in a variety of diseases, such as rickettsial infections,1 disseminated lupus erythematosus,2-4 periarteritis nodosa,5 malignancy,6 aplastic anemia7 and thrombotic thrombocytopenic purpura. The pathogenesis is as yet undetermined.
Moschcowitz8 was the first to report an instance of thrombotic thrombocytopenic purpura; this he did in 1925. He believed the thrombi consist of agglutinated erythrocytes, and pointed out that there is no evidence of primary vascular disease. Altschule9 ascribed the lesions to damage to the vascular endothelium, with secondary deposition of platelets. Muirhead and associates10 reported one case in
HUSEBYE KO, STICKNEY JM, BENNETT WA. "PLATELET" THROMBOSIS IN LEUKEMIA1. Ann Intern Med. ;44:975–984. doi: 10.7326/0003-4819-44-5-975
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Published: Ann Intern Med. 1956;44(5):975-984.
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