MARTIN KLEIN, M.D.; EDWARD C. BRESSLER, M.D.
The syndrome of unilateral optic atrophy with papilledema of the opposite eye was first described in association with basofrontal tumors of the brain by Paton in 1909.1 In 1911 Foster Kennedy,2 whose name has been affixed to this syndrome, presented six cases of basofrontal tumors having these findings, and stated ". . . (the syndrome) is decisively diagnostic in that it cannot possibly be simulated by any lesion failing to exert pressure on the inferior surface of one or other frontal lobe."
In the great majority of cases this statement has proved valid, but there have also been sporadic reports
KLEIN M, BRESSLER EC. OPTIC ATROPHY AND AN OCULAR COMPLICATION OF DIABETES MELLITUS SIMULATING THE FOSTER KENNEDY SYNDROME1. Ann Intern Med. 1956;44:1240–1249. doi: 10.7326/0003-4819-44-6-1240
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Published: Ann Intern Med. 1956;44(6):1240-1249.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Neurology.
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