BENJAMIN M. KAPLAN, M.D.; JULIUS S. NEWMAN, M.D.; ERVIN KAPLAN, M.D.; LYLE A. BAKER, M.D., F.A.C.P.; JOHN M. LEE, M.D.
Gradual thrombotic occlusion of the renal veins may be manifested by the nephrotic syndrome.1-9 The entity is characterized by anasarca, proteinuria, hypoproteinemia and hyperlipemia in a patient who usually has overt evidence of thrombotic phenomena. At autopsy the renal veins are occluded by premortem thrombi, and the kidneys are moderately enlarged, showing interstitial edema and fibrosis and tubular changes.
Thrombosis of the renal veins was reviewed by Abeshous5 in 1945. In the "primary type," usually seen during infancy, extrinsic factors do not give rise to the thromboses. The thrombotic process is initiated in the renal vein or the intrarenal tributaries.
KAPLAN BM, NEWMAN JS, KAPLAN E, BAKER LA, LEE JM. BILATERAL RENAL VEIN THROMBOSIS AND THE NEPHROTIC SYNDROME(BILATERAL RENAL VEIN THROMBOSIS AND THE NEPHROTIC SYNDROME*). Ann Intern Med. 1956;45:505–518. doi: 10.7326/0003-4819-45-3-505
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Published: Ann Intern Med. 1956;45(3):505-518.
Nephrology, Nephrotic Syndrome.
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