NANCY E. WARNER, M.D.; NATHAN B. FRIEDMAN, M.D.
Boeck's sarcoid, or true sarcoidosis, has been defined as a disease of unknown etiology, characterized pathologically by the presence in any organ or tissue of epithelioid cell tubercles with absent or inconspicuous necrosis. Refractile and apparently calcified bodies are frequently present in the giant cells of the tubercles, but acid-fast organisms are absent. The characteristic microscopic granulomas persist, although the lesions become scarred and hyalinized.
Many investigators have observed that there are a variety of agents which evoke a pattern of tissue reaction similar to the lesions seen in Boeck's sarcoid.1-4 Among these agents are acid-fast bacilli, including Mycobacterium tuberculosis
WARNER NE, FRIEDMAN NB. LIPOGRANULOMATOUS PSEUDOSARCOID1. Ann Intern Med. ;45:662–673. doi: 10.7326/0003-4819-45-4-662
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Published: Ann Intern Med. 1956;45(4):662-673.
Hospital Medicine, Pulmonary/Critical Care.
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