JOHN F. MURRAY, M.D.; S. FRED RABINER, M.D.; BERNARD KABAKOW, M.D.
Cortisone, hydrocortisone, and adrencorticotropic hormone (ACTH) have been employed therapeutically in a variety of blood dyscrasias.1 These compounds have been found particularly effective in thrombocytopenic purpura,2 acquired hemolytic anemias3 and, to a lesser extent, in acute leukemias.4 Recently several reports have suggested that cortisone and ACTH are useful, and may perhaps be life-saving, in the treatment of drug-induced agranulocytosis.5-9
The following is a report of a patient with marked bone marrow depression, possibly secondary to propylthiouracil administration, who showed an initial response to intravenous hydrocortisone and was subsequently successfully treated with ACTH.
A 36 year old white unmarried
JOHN F. MURRAY, S. FRED RABINER, BERNARD KABAKOW. BONE MARROW DEPRESSION SUCCESSFULLY TREATED WITH HYDROCORTISONE AND CORTICOTROPIN (ACTH)(BONE MARROW DEPRESSION SUCCESSFULLY TREATED WITH HYDROCORTISONE AND CORTICOTROPIN (ACTH)*). Ann Intern Med. 1957;46:387–391. doi: 10.7326/0003-4819-46-2-387
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Published: Ann Intern Med. 1957;46(2):387-391.
Hematology/Oncology, Hospital Medicine.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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