ARNOLD G. WARE, PH.D.; ROBERT STRAGNELL, M.D.
The theoretic possibility of controlling thrombo-embolic disease with agents that inhibit blood clotting is well recognized. There is no question that undesirable thrombotic complications can be prevented when anticoagulant agents are properly utilized. However, the dangers resulting from this type of treatment appear in the literature1 all too frequently. Dicumarol has earned the reputation of being one of the most dangerous drugs in common use.2 This is indeed unfortunate, because this drug can be administered safely and effectively.
One of the first essentials to successful anticoagulant therapy is proper laboratory control. There are very few situations in clinical medicine where
WARE AG, STRAGNELL R. ANTICOAGULANT THERAPY: ELIMINATION OF SOME COMMONLY OCCURRING PITFALLS1. Ann Intern Med. ;46:450–456. doi: 10.7326/0003-4819-46-3-450
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Published: Ann Intern Med. 1957;46(3):450-456.
Coagulopathies, Hematology/Oncology, Hospital Medicine.
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