WARREN N. BELL, M.D., D.SC. (Med.), F.R.C.P.(C); IRVING IMBER, M.D., F.A.C.P.
Defective platelet function has been postulated as the basic defect in pseudohemophilia.17 This is a hereditary hemorrhagic diathesis affecting either sex and characterized by a prolonged bleeding time, normal platelet count and normal clotting time. An intermittent course and spontaneous improvement in later life have been noted. A somewhat similar clinical picture has also been designated as "thrombasthenia" by other authors. Our results in a group of 27 such patients, using more definitive coagulation tests, demonstrated variable platelet dysfunction. Accordingly, we prefer the term "thrombasthenia" for such a syndrome, since it appears more descriptive. All patients demonstrated hyperheparinemia during active
BELL WN, IMBER I. A THROMBASTHENIC SYNDROME ASSOCIATED WITH HYPERHEPARINEMIA1. Ann Intern Med. ;46:537–545. doi: 10.7326/0003-4819-46-3-537
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Published: Ann Intern Med. 1957;46(3):537-545.
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