LEONARD B. BERMAN, M.D.; GEORGE E. SCHREINER, M.D.; JEAN FEYS, M.D.
Needle biopsy of the kidney affords a unique opportunity to study the pathology of renal disease in the living patient.1 This relatively new and valuable investigative tool was employed in one of two recently observed nonfatal cases of acute renal insufficiency due to ethylene glycol. The demonstration of oxalate crystals in the renal tubules represents the first reported premortem confirmation of a finding well established in autopsy material.2 Observations on additional histologic changes and clinical course manifested by these patients may be of sufficient interest to warrant a description and brief review of ethylene glycol toxicity.
Ethylene glycol was first
BERMAN LB, SCHREINER GE, FEYS J. THE NEPHROTOXIC LESION OF ETHYLENE GLYCOL1. Ann Intern Med. ;46:611–619. doi: 10.7326/0003-4819-46-3-611
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Published: Ann Intern Med. 1957;46(3):611-619.
Hospital Medicine, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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