ROBERTO F. ESCAMILLA, M.D., F.A.C.P.; C. HENRY KEMPE, M.D.; JACKSON CRANE, M.D.; LEON GOLDMAN, M.D., F.A.C.S.; GILBERT S. GORDAN, M.D., F.A.C.P.
A number of attempts to transplant parathyroid tissue into patients with hypoparathyroidism have been made in the past. Results have not been consistent, although occasional isolated successes have been reported. In a review of the problem in 1933, Stone, Owings and Gey1 mentioned tissue culture adaptation with host serum as a possible solution, and expressed the hope that many endocrine deficiencies might be treated by grafts of living tissue. More recently, Gaillard,2-4 crediting Gassul5 and Erdmann6 with the idea of attempting to "adapt" explants to the humoral milieu of the future host in tissue culture, reported the results of transplants
ESCAMILLA RF, KEMPE CH, CRANE J, GOLDMAN L, GORDAN GS. PRELIMINARY EXPERIENCES WITH TRANSPLANTS OF CULTURED PARATHYROID TISSUE IN HYPOPARATHYROIDISM1. Ann Intern Med. ;46:649–661. doi: 10.7326/0003-4819-46-4-649
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Published: Ann Intern Med. 1957;46(4):649-661.
Endocrine and Metabolism, Parathyroid Disorders.
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