A. J. REICHES, M.D.
The apparent increasing frequency of the lupus erythematosus syndrome and the discovery by Hargraves1 of a cell in the peripheral blood and bone marrow facilitating its diagnosis have greatly stimulated interest in this disease entity. One might, with reservations, compare such increased interest with that shown in the past toward the varied manifestations of syphilis.
The term lupus erythematosus was introduced by Cazenave2 in 1851 to describe the skin lesions of fixed erythema, follicular plugging, adherent scaling, atrophy and telangiectasia. Subsequently Kaposi3 postulated a relationship of the cutaneous lesion to the acute systemic disseminated disease. He noted that the characteristic
REICHES AJ. THE LUPUS ERYTHEMATOSUS SYNDROME: THE RELATIONSHIP OF DISCOID (CUTANEOUS) LUPUS ERYTHEMATOSUS TO SYSTEMIC (DISSEMINATED) LUPUS ERYTHEMATOSUS1. Ann Intern Med. 1957;46:678–684. doi: 10.7326/0003-4819-46-4-678
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Published: Ann Intern Med. 1957;46(4):678-684.
Lupus Erythematosus, Rheumatology.
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