MICHAEL G. WOHL, M.D., F.A.C.P.; CHARLES R. SHUMAN, M.D., F.A.C.P.
Unrecognized hyperthyroidism may progress insidiously to an advanced phase of the disease. The atypical syndromes disguising the true nature of the process are varied, with manifestations related to other organ systems diverting attention from the underlying metabolic disturbance. The variations in the clinical picture may frequently lead to errors in diagnosis when their nature remains obscure. Virtually any organ or system may present abnormalities simulating primary disease within it as a result of the adverse influence of hyperthyroidism upon its function.
Among cases which have been found to produce considerable difficulty in diagnosis are those with involvement of the cardiovascular
WOHL MG, SHUMAN CR. ATYPICAL SYNDROMES IN HYPERTHYROIDISM1. Ann Intern Med. ;46:857–867. doi: 10.7326/0003-4819-46-5-857
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Published: Ann Intern Med. 1957;46(5):857-867.
Endocrine and Metabolism, Thyroid Disorders.
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