IRVING A. FRIEDMAN, M.D.; JEROME F. SICKLEY, M.D.; ROBERT M. POSKE, M.D.; ARNOLD BLACK, M.D.; DAVID BRONSKY, M.D.; WILSON H. HARTZ JR., M.D.; CHARLOTTE FELDHAKE, B.S.; PAUL S. REEDER, M.D.; ELI M. KATZ, M.D.
The specificity of the lupus erythematosus phenomenon for the diagnosis of systemic lupus erythematosus has been emphasized by many investigators.1, 7 Nevertheless, occasional reports continue to appear describing this phenomenon in diseases other than systemic lupus erythematosus. Positive reactions have been reported in isolated cases of periarteritis nodosa,8 thrombotic thrombocytopenic purpura,9 tuberculosis10, 11 and postnecrotic cirrhosis.12, 13 The phenomenon has been reported after hypersensitivity reactions to penicillin,14, 15 tetanus antitoxin,16 phenylbutazone17 and following the administration of hydralazine18, 19, 20 and prolonged steroid therapy.21, 22 The presence of L. E. cells has been mentioned but not thoroughly differentiated from nucleophagocytosis in
FRIEDMAN IA, SICKLEY JF, POSKE RM, BLACK A, BRONSKY D, HARTZ WH, et al. THE L. E. PHENOMENON IN RHEUMATOID ARTHRITIS1. Ann Intern Med. ;46:1113–1136. doi: 10.7326/0003-4819-46-6-1113
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Published: Ann Intern Med. 1957;46(6):1113-1136.
Rheumatoid Arthritis, Rheumatology.
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