WILLIAM F. LUTTGENS
No reports of this complication of thrombotic thrombocytopenic purpura were found in a review of the literature. Somewhat similar skin lesions were described, however, in two cases in which the patients eventually recovered. In the case reported by Jernigan and Farber1 there were many features in common with the case herein reported. In the case they described, a 36 year old woman had recurrent malaise, chills, fever, thrombocytopenia, anemia, leukopenia, and hemorrhagic necrosis of the skin and subcutaneous tissue over a period of four years. There was good response to cortisone in a dosage up to 800 mg. daily. Skin
LUTTGENS WF. THROMBOTIC THROMBOCYTOPENIC PURPURA WITH EXTENSIVE HEMORRHAGIC GANGRENE OF THE SKIN AND SUBCUTANEOUS TISSUE: REPORT OF A CASE(THROMBOTIC THROMBOCYTOPENIC PURPURA WITH EXTENSIVE HEMORRHAGIC GANGRENE OF THE SKIN AND SUBCUTANEOUS TISSUE: REPORT OF A CASE*). Ann Intern Med. 1957;46:1207–1213. doi: 10.7326/0003-4819-46-6-1207
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Published: Ann Intern Med. 1957;46(6):1207-1213.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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