G. LENNARD GOLD, M.D.; RICHARD D. FRITZ, M.D.
Elevations of serum and urinary concentrations of uric acid have been described in acute leukemia.1, 2 It is also known that, with therapy, urate excretion may rise.3, 4, 5, 6 Recently the authors have had an opportunity to view two patients who showed a marked degree of hyperuricemia concomitant with therapy of their acute lymphocytic leukemia. The authors thought that a review of these cases might point out a hazard in treating these patients.
Case 1. A 50 year old white female housewife had been well until the winter of 1954, when she developed unusual fatigue and a
GOLD GL, FRITZ RD. HYPERURICEMIA ASSOCIATED WITH THE TREATMENT OF ACUTE LEUKEMIA(HYPERURICEMIA ASSOCIATED WITH THE TREATMENT OF ACUTE LEUKEMIA*). Ann Intern Med. 1957;47:428–434. doi: 10.7326/0003-4819-47-3-428
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Published: Ann Intern Med. 1957;47(3):428-434.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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