CARL F. HINZ JR., M.D.
Since the introduction of specific therapy for pernicious anemia, persons with this disease have lived sufficiently long to develop other disorders of the hematopoietic system. A striking but distinctly unusual instance of this has been the development in such patients of polycythemia vera. Such cases would appear to be interesting in light of the frequent speculation concerning the etiology and pathogenesis of pernicious anemia and polycythemia rubra vera.
A review of the literature reveals several instances of polycythemia developing in association with liver therapy, and a few cases of typical polycythemia vera associated with or following treatment for classic
HINZ CF. FATAL POLYCYTHEMIA FOLLOWING PERNICIOUS ANEMIA TREATED WITH VITAMIN B121. Ann Intern Med. ;47:544–552. doi: 10.7326/0003-4819-47-3-544
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Published: Ann Intern Med. 1957;47(3):544-552.
Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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