EDWARD M. SCHNEIDER, M.D.; MERVIN L. CLARK, M.D.
Rauwolfia and its various alkaloids have been recommended in the treatment of gastrointestinal syndromes because of their tranquilizing effects. But their stimulating effects on gastric secretion have made it difficult to determine the indications for their use.
I. Studies with Intravenous Reserpine: The methods used in these studies have been previously reported.1, 2 Briefly, all subjects were studied after an overnight fast. A Levin tube was placed in the stomach and in every instance
baseline determinations of gastric acid were made over a 30- to 90-minute period prior to the administration of any agent, placebo or otherwise.
a. Figure 1
SCHNEIDER EM, CLARK ML. GASTRIC SECRETION AS INFLUENCED BY RAUWOLFIA ALKALOIDS1. Ann Intern Med. ;47:640–650. doi: 10.7326/0003-4819-47-4-640
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Published: Ann Intern Med. 1957;47(4):640-650.
Gastroenterology/Hepatology, Hospital Medicine, Peptic Disease, Peptic Ulcer.
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