The increasing importance of atherosclerosis as a cause of death has intensified interest in this serious disturbance and stimulated extensive investigations. One major phase of this subject now under active study and debate is the relationship of cholesterol and other lipids to atherosclerosis, both as a possible causative factor and as an indicator or predictor of existing or impending disease.
In patients with ordinary atherosclerosis a high concentration of cholesterol is found in many individuals, and levels significantly above normal have been reported in many studies of such groups. Some of the earlier reports we have previously reviewed here.1 There
THE VALUE OF DETERMINATIONS OF CHOLESTEROL AND OF LIPOPROTEINS OF LOW DENSITY IN THE BLOOD AS PREDICTORS OF OVERT ATHEROSCLEROSIS. Ann Intern Med. ;47:841–845. doi: 10.7326/0003-4819-47-4-841
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Published: Ann Intern Med. 1957;47(4):841-845.
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