DAVID P. BARR, M.D., M.A.C.P.; RALPH L. ENGLE JR., M.D.; ELLA M. RUSS, B.S., D.SC.
The following case report illustrates difficulties that may be encountered when a large amount of cold precipitable globulin circulates in the blood of a patient with the malady which has been called cryoglobulinemia.1, 2
A single man of 50 was referred to The New York Hospital by Dr. Robert Nickau, of Jacksonville, Florida. He had been well until 1946, when he noted severe aching pain in his fingers. This became more severe on exposure to cold and subsided when he was in a hot environment. During the winter the pain was more persistent and was accompanied by intense
BARR DP, ENGLE RL, RUSS EM. CRYOGLOBULINEMIA: A CASE REPORT1. Ann Intern Med. ;47:1225–1234. doi: 10.7326/0003-4819-47-6-1225
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Published: Ann Intern Med. 1957;47(6):1225-1234.
CNS Infections, Hematology/Oncology, Hospital Medicine, Infectious Disease, Multiple Myeloma.
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