JOAQUIN F. LOPEZ, M.D.
Pheochromocytoma today cannot be considered an unusually rare tumor, since numerous isolated cases as well as small series have been reported. In 1952 Aaron1 stated that about 300 cases had been published, but that they probably represent but a small fraction of the actual number.
The association of pheochromocytoma with a malignant neoplasia, however, is much more infrequent. Four cases have been reported associated with neuroblastomas.2, 3, 4, 5 One case had a "neurogenic sarcoma,"6 one a carcinoma of the rectum,7 and another a neurofibromatosis with "malignant degeneration."8 The second case of Mandeville and Sahyoun9 and the recent one of
LOPEZ JF. PHEOCHROMOCYTOMA OF THE ADRENAL GLAND WITH GRANULOSA CELL TUMOR AND NEUROFIBROMATOSIS: REPORT OF A CASE WITH FATAL OUTCOME FOLLOWING ABDOMINAL AORTOGRAPHY1. Ann Intern Med. ;48:187–199. doi: 10.7326/0003-4819-48-1-187
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Published: Ann Intern Med. 1958;48(1):187-199.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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