JULIUS J. CHOSEY, M.D.; FLOYD M. BEMAN, M.D.
Jaundice is ordinarily considered to be a sign of altered bilirubin metabolism. The significance of this symptom is evident when one considers the elaborate studies carried out in an attempt to clarify the mechanism in any given case. Occasionally the opportunity arises to study a patient with jaundice who apparently does not fit into any of the standard categories, and in whom the presence of an elevated bilirubin is compatible with good health.
Constitutional hepatic dysfunction was probably first described by Gilbert and his associates in 1902. Since that time, several excellent reviews of this subject have been presented,
CHOSEY JJ, BEMAN FM. CONSTITUTIONAL HEPATIC DYSFUNCTION(CONSTITUTIONAL HEPATIC DYSFUNCTION*†)(CONSTITUTIONAL HEPATIC DYSFUNCTION*†). Ann Intern Med. 1958;48:202–205. doi: 10.7326/0003-4819-48-1-202
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Published: Ann Intern Med. 1958;48(1):202-205.
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