ALVAN R. FEINSTEIN, M.D.; VINCENT P. DOLE, M.D.; IRVING L. SCHWARTZ, M.D.
Total replacement of natural food by a nutrient mixture was used for weight reduction of obese patients almost a century ago. In 1866 Karell1 described a liquid diet providing only three or four glasses of creamy milk per day, taken at carefully observed intervals. In 1908 Moritz2 reported treatment of nine obese patients with whole milk or buttermilk given as the sole nutriment for periods of up to 61 days. Harrop3 in 1934 recommended the use for two-week periods of a skimmed-milk-and-banana diet alternated with a conventional, calorically-restricted mixed-food diet. The majority of patients in each of these studies accepted
ALVAN R. FEINSTEIN, VINCENT P. DOLE, IRVING L. SCHWARTZ. THE USE OF A FORMULA DIET FOR WEIGHT REDUCTION OF OBESE OUT-PATIENTS(THE USE OF A FORMULA DIET FOR WEIGHT REDUCTION OF OBESE OUT-PATIENTS*). Ann Intern Med. 1958;48:330–343. doi: 10.7326/0003-4819-48-2-330
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Published: Ann Intern Med. 1958;48(2):330-343.
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