WILLIAM DAMESHEK, M.D., F.A.C.P.
Systemic (disseminated) lupus erythematosus has been known for at least 50 years, but its exact nature and the pathogenetic mechanisms bringing it about are almost as obscure now as they were when the disease was first described. Considered a rarity for the first three decades of the present century, its incidence seems to be increasing steadily, although whether this is actually so or the result of better recognition is difficult to state.
Systemic lupus must still be classed as a complex disorder of obscure origin. Even its histopathology has been in doubt, often in the hands of the same
WILLIAM DAMESHEK. SYSTEMIC LUPUS ERYTHEMATOSUS: A COMPLEX AUTO-IMMUNE DISORDER?(SYSTEMIC LUPUS ERYTHEMATOSUS: A COMPLEX AUTO-IMMUNE DISORDER?*†)(SYSTEMIC LUPUS ERYTHEMATOSUS: A COMPLEX AUTO-IMMUNE DISORDER?*†). Ann Intern Med. 1958;48:707–730. doi: 10.7326/0003-4819-48-4-707
Download citation file:
Published: Ann Intern Med. 1958;48(4):707-730.
Lupus Erythematosus, Rheumatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use