IRVING L. BINDELGLASS, M.D.; SIDNEY TRUBOWITZ, M.D., F.A.C.P.
The mediastinum in health is an extremely mobile and adaptable space lined by a minimum of connective tissue which binds together the heart, great vessels, esophagus, trachea, lymphatic channels and the phrenic and vagus nerves. This adaptability to the changes in size, shape and position of the mediastinal structures may be seriously impaired by various pathologic processes, including inflammation and neoplasm. Thus, in chronic mediastinitis, the laying down of dense connective tissue may lead to the production of striking and dramatic symptom complexes as a result of compression of one or more of these structures. Some of the sequelae of
BINDELGLASS IL, TRUBOWITZ S. PULMONARY VEIN OBSTRUCTION: AN UNCOMMON SEQUEL TO CHRONIC FIBROUS MEDIASTINITIS1. Ann Intern Med. 1958;48:876–891. doi: 10.7326/0003-4819-48-4-876
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Published: Ann Intern Med. 1958;48(4):876-891.
Hospital Medicine, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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