GARY ZUCKER, M.D., F.A.C.P.; JULES LEVINE, M.D.
A solitary pulsating tumor of bone is a rare occurrence. It is important clinically in that it usually represents a metastasis from a carcinoma of the kidney or thyroid.1 The primary tumor itself may be entirely asymptomatic.
According to Willis,1 the first case of pulsating metastases was described by Morris2 in 1880. The patient was observed for six years, during which time she developed pulsating tumors in the parietal bone, the clavicle and both hips. At autopsy, the metastatic lesions had the colloid vesicular structure of thyroid carcinoma. Since then additional cases have been reported sporadically in the medical literature.3-14
GARY ZUCKER, JULES LEVINE. PULSATING METASTASIS OF THE FEMUR FROM A SILENT HYPERNEPHROMA(PULSATING METASTASIS OF THE FEMUR FROM A SILENT HYPERNEPHROMA*). Ann Intern Med. 1958;48:897–902. doi: 10.7326/0003-4819-48-4-897
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Published: Ann Intern Med. 1958;48(4):897-902.
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