JOHN H. BLAND, M.D., F.A.C.P.; ROBERT O'BRIEN, M.D.; RICHARD E. BOUCHARD, M.D.
Save for the extensive observations and investigations of Dr. William B. Bean, the physical signs of palmar erythema and spider angiomata have received little clinical attention or interpretation. The forces producing them remain obscure. Their possible significance in diagnosis and therapy is an interesting, if diminutive, field for speculation.
Their appearance in a variety of disease states as well as in physiologic conditions—namely, pregnancy and normal aging—makes their observation and study a worth while project. They may provide foundation for important research; their proper interpretation currently has clinical usefulness. Spider angiomata have been most noted in chronic liver disease. Palmar
BLAND JH, O'BRIEN R, BOUCHARD RE. PALMAR ERYTHEMA AND SPIDER ANGIOMATA IN RHEUMATOID ARTHRITIS1. Ann Intern Med. 1958;48:1026–1032. doi: 10.7326/0003-4819-48-5-1026
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Published: Ann Intern Med. 1958;48(5):1026-1032.
Rheumatoid Arthritis, Rheumatology.
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