RICHARD P. SPENCER; E. RICHARD KING; CHARLES R. HENKELMANN; THEODORE G. BALBUS
A useful concept in orienting our thinking about the thyroid is to consider its parameters. The term parameter has gained use in medicine to indicate an arbitrary test for quantitating some aspect of metabolism. For instance, to study the thyroid we can employ such determinations as the basal metabolic rate. But do these arbitrary procedures measure thyroid activity and, if so, can such activity be quantitated? This paper is concerned with an evaluation of parameters proposed for studying the thyroid gland.
To be valid, a test of thyroid activity must fulfill two requirements. First, it should measure a function that
SPENCER RP, KING ER, HENKELMANN CR, BALBUS TG. A DISCUSSION OF THYROID PARAMETERS1. Ann Intern Med. ;48:1046–1054. doi: 10.7326/0003-4819-48-5-1046
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Published: Ann Intern Med. 1958;48(5):1046-1054.
Endocrine and Metabolism, Thyroid Disorders.
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