RAY L. CASTERLINE, M.D., F.A.C.P.
The current medical literature has been adequately documented with specific instances of profound allergic reaction to penicillin and other antimicrobial agents.1, 2 This case is presented to emphasize that allergic reactions to tetanus antitoxin do occur in spite of apparently adequate testing with horse serum prior to administration of the antitoxin. These reactions, when they occur, often fit the picture of serum sickness and may involve wide areas. They are often basically vascular in nature3 and capable of producing considerable injury in the areas affected by the vascular phenomena, although most of the lesions appear to be reversible. This case
CASTERLINE RL. MYOCARDIAL ISCHEMIA: REPORT OF A CASE DUE TO REACTION TO TETANUS ANTITOXIN1. Ann Intern Med. ;48:1121–1125. doi: 10.7326/0003-4819-48-5-1121
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Published: Ann Intern Med. 1958;48(5):1121-1125.
Cardiology, Coronary Heart Disease.
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