S. P. BESSMAN, M.D.
It has been known for a long time that diabetes mellitus often showed a familial tendency and that to some extent this same tendency was present in other rarer melliturias. Only recently, however, have some of the genetic defects underlying the appearance of these sugars in the urine been brought to light.
Intricate and manifold in their metabolic pathways, the simple sugars of nutrition have been found to influence far more than the blood and urine sugar concentration. Clinical conditions such as cirrhosis, mental deficiency, cataract, and hemolytic anemia are now known to result, in some cases, from clearly defined
BESSMAN SP. GENETICS AND GLYCOLYSIS. Ann Intern Med. ;48:1146–1150. doi: 10.7326/0003-4819-48-5-1146
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Published: Ann Intern Med. 1958;48(5):1146-1150.
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