I. DARIN PUPPEL, M.D.; E. K. MCCORMICK, M.S.; E. HERDLE, M.S.
Our knowledge concerning the influence of calcium, phosphorus and vitamin D administration on hyperthyroidism is as yet meager and, at times, confusing. The exact mechanism of action of calcium and phosphorus and their consequent therapeutic indications in the management of patients with hyperthyroidism are not fully understood, despite the fact that calcium has been employed in this condition by experienced clinicians, including Theodore Kocher, for many years.44, 51, 7, 41 In fact, certain investigators27, 28 have expressed doubt that added calcium would be beneficial in counteracting the negative calcium balance of this disease, although their investigations had not extended this
PUPPEL ID, MCCORMICK EK, HERDLE E. SOME METABOLIC FACTORS IN THE TREATMENT OF HYPERTHYROIDISM1. Ann Intern Med. ;48:1300–1327. doi: 10.7326/0003-4819-48-6-1300
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Published: Ann Intern Med. 1958;48(6):1300-1327.
Endocrine and Metabolism, Thyroid Disorders.
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