JOSEPH J. KAUFMAN, M.D.; WILLARD E. GOODWIN, M.D.
In previous publications1, 2 the function of renal lymphatics in homeostasis of the kidney is discussed. We believe that the renal lymphatics act as a "safety valve" for the kidneys under conditions of diuresis and/or ureteral obstruction. There is experimental support for this idea.3-6
This collateral pathway for the escape of fluid from the kidney operates under conditions of ureteral obstruction to prevent the kidney from self-destruction. This function of the renal lymphatics may be an important factor in total renal function in a variety of diseases such as nephrosis, pyelonephritis, orthostatic albuminuria, chyluria, and possibly congestive heart failure.
KAUFMAN JJ, GOODWIN WE. RENAL LYMPHATICS. III. CLINICAL IMPLICATIONS AND EXPERIMENTS OF NATURE(RENAL LYMPHATICS. III. CLINICAL IMPLICATIONS AND EXPERIMENTS OF NATURE*). Ann Intern Med. 1958;49:109–119. doi: 10.7326/0003-4819-49-1-109
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Published: Ann Intern Med. 1958;49(1):109-119.
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