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In March of 1957 a symposium on the mechanisms of development of drug resistance in micro-organisms was held under the auspices of the Ciba Foundation. This book is the record of the papers presented with the discussion of those papers.
Dean, Hinshelwood, Demerec, Cavalli-Sforza, Lederberg, Hughes, Yudkin, Davis, Hayes are some of the expert men in this field who participated.
The battle line is immediately drawn between those who maintain that bacterial resistance is a function of random mutation with environmental selection and those who hold that physiological adaptation is the mechanism of resistance. This mutation-adaptation controversy motivates the conference
Drug Resistance in Micro-Organisms: Mechanisms of Development.. Ann Intern Med. ;49:229–230. doi: 10.7326/0003-4819-49-1-229_3
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Published: Ann Intern Med. 1958;49(1):229-230.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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