MARTIN J. FITZPATRICK, M.D.; HARRY RUBIN, M.D.; CHARLES M. POSER, M.D.
In recent years there has been a growing medical awareness of the prevalence of chronic systemic fungus infections, many of which are worldwide in distribution.1 In addition to the more readily apparent cutaneous and osseous infections, deep mycotic infections involving the pulmonary, renal, gastrointestinal and central nervous systems are being reported with increasing frequency.2 During this time the continuing introduction of potent antibiotics and their enlarging clinical use have resulted in apparent control of many important bacterial infections, with a shifting spectrum of infectious diseases in many communities. As a result of this changing background, chronic fungus infections have
FITZPATRICK MJ, RUBIN H, POSER CM. THE TREATMENT OF CRYPTOCOCCAL MENINGITIS WITH AMPHOTERICIN B, A NEW FUNGICIDAL AGENT1. Ann Intern Med. ;49:249–259. doi: 10.7326/0003-4819-49-2-249
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Published: Ann Intern Med. 1958;49(2):249-259.
CNS Infections, Infectious Disease, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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