GORDON MEIKLEJOHN, M.D.; ALTON J. MORRIS, M.D.
Attempts to prevent influenza by vaccination began slightly more than 15 years ago. In the winter of 1943-44 a significant reduction in the incidence of influenza A by vaccination was demonstrated in multiple field trials carried out by the Commission on Influenza, Armed Forces Epidemiological Board.1 Two years later, protection of even higher order was observed with influenza B vaccine.2, 3 It appeared at that time that the problem of providing a high degree of protection against both influenza A and B might be solved with relative ease. Then, in 1947, influenza A-prime strains appeared, and it became clear that
MEIKLEJOHN G, MORRIS AJ. INFLUENZA VACCINATION1. Ann Intern Med. ;49:529–535. doi: 10.7326/0003-4819-49-3-529
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Published: Ann Intern Med. 1958;49(3):529-535.
Infectious Disease, Influenza, Prevention/Screening, Vaccines/Immunization.
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