JOHN J. MCHUGH, M.D.; RAYMOND C. MELLINGER, M.D.
Endocrine exophthalmos can occur with or without evident hyperthyroidism, or may develop only after therapeutically induced remission of the thyrotoxicosis. The cause of the disorder has not been completely explained, but a pituitary factor, either thyrotropin or a physiologically related substance, is thought to be involved in its pathogenesis. The unusual history is presented of a patient who developed severe infiltrative ophthalmopathy 12 years after thyroidectomy. The normal pituitary-thyroid relationship associated with the exophthalmos is a significant feature of the case study.
A 62 year old housewife was first examined at the Henry Ford Hospital in January, 1957,
MCHUGH JJ, MELLINGER RC. PROGRESSIVE EXOPHTHALMOS DEVELOPING 12 YEARS AFTER THYROIDECTOMY FOR DIFFUSE TOXIC GOITER1. Ann Intern Med. 1958;49:955–958. doi: 10.7326/0003-4819-49-4-955
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Published: Ann Intern Med. 1958;49(4):955-958.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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