ROBERT S. NELSON, M.D., F.A.C.P.; VASANT M. DOCTOR, Ph.D.
The vitamin B12 content of human liver postmortem specimens has been previously studied,1, 8 and changes have been noted in pernicious anemia in relapse1 and in cirrhosis.8 These valuable contributions were necessarily of a static nature, and defined the liver vitamin B12 content after death in certain patients who could not be followed by serial determinations during life. Studies with radioactive labeled vitamin B122, 4, 5, 7 have done much to clarify the relative contents of various body organs and the rate at which absorption takes place from the bowel and parenterally. It has been shown that, in the human,
NELSON RS, DOCTOR VM. THE VITAMIN B12 CONTENT OF HUMAN LIVER AS DETERMINED BY BIO-ASSAY OF NEEDLE BIOPSY MATERIAL12. Ann Intern Med. ;49:1361–1367. doi: 10.7326/0003-4819-49-6-1361
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Published: Ann Intern Med. 1958;49(6):1361-1367.
Gastroenterology/Hepatology, Liver Disease.
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