MONROE THOMAS DIAMOND, M.D., F.A.C.P.
Although hypertrophic osteoarthropathy has been noted in association with a wide variety of primary disorders,1 its occurrence with diseases of the thyroid has been little mentioned in the literature. In 1919 Ebstein2 briefly reported a case of clubbing of the fingers developing in a 24 year old male following thyroidectomy for exophthalmic goiter. Thomas3 in 1933 described in detail a patient who, eight months after having had a subtotal thyroidectomy for exophthalmic goiter, developed progressive hypertrophic osteoarthropathy and a concurrent brawny and pigmented edema of the legs consistent with myxedema. Thomas felt that the rapid change in thyroid function following
DIAMOND MT. THE SYNDROME OF EXOPHTHALMOS, HYPERTROPHIC OSTEOARTHROPATHY AND LOCALIZED MYXEDEMA: A REVIEW OF THE LITERATURE AND REPORT OF A CASE*. Ann Intern Med. ;50:206–213. doi: 10.7326/0003-4819-50-1-206
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Published: Ann Intern Med. 1959;50(1):206-213.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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